ANDROMEDA-SHOCK - Capillary Refill vs. Lactate

ANDROMEDA-SHOCK - Capillary Refill vs. Lactate

Peripheral perfusion guided resuscitation was better than lactate clearance in patients with septic shock in regard to improving organ dysfunction at 72 hours (SOFA score) and barely missed statistical significance in reducing 28-day mortality.

Multiplex PCR in Critically Ill Hematology Patients

Multiplex PCR in Critically Ill Hematology Patients

Presence of any virus on multiplex PCR (particularly influenza, parainfluenza, and RSV) in critically ill hematology patients was associated with an increased risk for respiratory failure and ICU mortality.

PRIME RCT - Ketamine or Fentanyl Intranasal For Pediatric Injuries?

PRIME RCT - Ketamine or Fentanyl Intranasal For Pediatric Injuries?

Intranasal ketamine is noninferior to intranasal fentanyl for pain associated with pediatric extremity injuries. However, there is a higher risk of minor adverse events.

Can We Use Ondansetron In Pregnancy?

Can We Use Ondansetron In Pregnancy?

In this large cohort study of over 1.8 million pregnancies, first trimester ondansetron use was not associated with cardiac malformations or total congenital malformations. However, there was a small increased risk of oral clefts (3 additional cases per 10,000 women treated).

Is This Patient Really Penicillin Allergic?

Is This Patient Really Penicillin Allergic?

Penicillin allergy is a lot less common than patients report. A low-risk history could allow you to prescribe it in the ED or clinic.

Pediatric Needle Decompression - What Size Needle?

Pediatric Needle Decompression - What Size Needle?

A standard 5cm 14-16 gauge needle for chest decompression was more than twice as long as needed for children < 13 years old based on CT chest wall thickness (CWT).

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