Do All Children Admitted with CAP Need a Blood Culture?

Do All Children Admitted with CAP Need a Blood Culture?

Overall yield of blood culture for pediatric community acquired pneumonia (CAP) was low; 91 blood cultures were needed to get one positive result. But in children admitted to the ICU, one child had bacteremia for every 24 cultures obtained; one for every 12 in children with parapneumonic effusion.

EcLiPSE - Should Levetiracetam Replace Phenytoin for Pediatric Status Epilepticus?

EcLiPSE - Should Levetiracetam Replace Phenytoin for Pediatric Status Epilepticus?

There was no difference in levetiracetam vs phenytoin as second-line agents after benzodiazepines for pediatric status epilepticus in median time to seizure cessation. Levetiracetam may have other advantages, as it is able to be given over 5 minutes (vs 20 minutes for phenytoin) and causes fewer adverse effects.

HEART and High Sensitivity Troponin

HEART and High Sensitivity Troponin

Combining a Δ1h high-sensitivity troponin (hsTn) with the HEART score in a diagnostic algorithm helped decrease admission rates (59% to 33%) and median health-care costs ($1,748 to $1,079) with no significant difference in clinical outcomes. It is important to realize that this study was not randomized and was underpowered to detect differences in clinical outcome.

Do We Still Need Annual TB Skin Testing?

Do We Still Need Annual TB Skin Testing?

The CDC no longer recommends* annual TB screening of health care providers in the absence of a known exposure or ongoing transmission.

Door-to-Antibiotic And Mortality in Sepsis

Door-to-Antibiotic And Mortality in Sepsis

Mortality was higher when door-to-antibiotic time was > 3 h. However, there was no difference when comparing mortality in those given antibiotics within the first hour to those after the first hour.

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