Administration of plasma first for traumatic hemorrhagic shock when brought by ground did not change 28-day mortality.
Epinephrine for out-of-hospital cardiac arrest improved overall 30-day survival (3.2%, epi vs 2.4%, placebo) but did not improve survival to discharge with a good neurological outcome. In fact, more patients who received epinephrine and survived had severe neurological impairment than in the placebo group.
Delayed ROSC may occur after cessation of CPR - the so called Lazarus phenomenon. The incidence is around 6/1000 cases and usually occurred within 3-8 minutes after CPR cessation. All patients eventually died; 4 of 5 had PEA. It may be wise to allow 10 minutes before pronouncing death (or 4 days if the patient is actually named Lazarus).