Do Probiotics Plus Antibiotics Prevent C. difficile?

Do Probiotics Plus Antibiotics Prevent C. difficile?

Probiotics decrease the risk of C. difficile infection in adults and children taking antibiotics and may reduce overall adverse events like cramping, nausea, or diarrhea.

Does This Patient Have Pertussis? Bedside Clues to Diagnosis

Does This Patient Have Pertussis? Bedside Clues to Diagnosis

Adults with cough <3weeks or 3-8 weeks with post-tussive vomiting or whooping should be treated for pertussis; those with fever or without paroxysmal cough should be considered to have an alternate diagnosis. Children with <4 weeks of cough and post-tussive vomiting may have pertussis, but it was much less clear than in adults.

Do We Write Antibiotic Rx Because It's Just Easier?

Do We Write Antibiotic Rx Because It's Just Easier?

It took an extra 67 seconds when not prescribing an antibiotic to patients with acute respiratory infection compared to visits in which an antibiotic was prescribed.

Do Antiarrhythmic Drugs Help In Cardiac Arrest?

Do Antiarrhythmic Drugs Help In Cardiac Arrest?

When considering 14 RCTs on use of antiarrhythmic drugs for shockable cardiac arrest, there was no benefit for survival to discharge or survival with good neurological outcome. Lidocaine improved ROSC vs placebo.

Initial Parenteral then Oral Antibiotic vs Oral Alone in Pediatric UTI

Initial Parenteral then Oral Antibiotic vs Oral Alone in Pediatric UTI

There was no reduction in children 29 days - 2 months in 72-hour repeat ED visit with subsequent admission for those given a single parenteral dose of antibiotic in the ED and then outpatient oral treatment vs simply starting on oral therapy.

Pediatric TBI Guidelines from the CDC

Pediatric TBI Guidelines from the CDC

Taking care of children with mild traumatic brain injury is not easy. This guideline states clearly, based on compiled evidence, what you should and should not do.  It’s helpful.

Antibiotic Harms - 70,000 PED Visits a Year

Antibiotic Harms - 70,000 PED Visits a Year

Adverse drug events related to antibiotics led to nearly 70,000 ED visits a year in children ≤19 years.  One out of every 330 children ≤2 years given amoxicillin will end up in the ED with an ADE.

New Risk After TBI - Suicide

New Risk After TBI - Suicide

The incidence of suicide nearly doubled in patients who had traumatic brain injury (TBI) compared to baseline.  Risk increased with severity of injury, number of visits, and was highest in the first 6 months post-injury.

Do Steroids Benefit Influenza Pneumonia?

Do Steroids Benefit Influenza Pneumonia?

Unless there is compelling alternative reason to do so (i.e. asthma), giving a glucocorticoid to treat influenza pneumonia was associated with increased risk of mortality.

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