Prevalence of UTI With Bronchiolitis
When UTI was defined as a positive urine culture plus abnormal UA, the prevalence of concomitant UTI in febrile infants with bronchiolitis was 0.8% - below the usual testing threshold.
Multiplex PCR in Critically Ill Hematology Patients
Presence of any virus on multiplex PCR (particularly influenza, parainfluenza, and RSV) in critically ill hematology patients was associated with an increased risk for respiratory failure and ICU mortality.
Is This Patient Really Penicillin Allergic?
Penicillin allergy is a lot less common than patients report. A low-risk history could allow you to prescribe it in the ED or clinic.
I&D Only or Add Antibiotics?
Treating skin and soft tissue abscesses with antibiotics in addition to incision and drainage (I&D) resulted in significantly increased clinical cure rate (NNT = 14) and decreased incidence of new lesions (NNT = 10) compared to I&D alone.
When Will Oral Antibiotics for Cellulitis Fail?
”Tachypnea at triage, chronic ulcers, history of MRSA colonization or infection, and cellulitis within the past year,” were the risk factors associated with failure of oral antibiotic therapy for non-purulent cellulitis.
New IDSA Influenza Guidelines
This is the IDSA influenza guideline, updated from the previous one in 2009. It covers testing, treatment, complications, and more.
Is Routine Pelvic Exam Beneficial for STI Detection?
Pelvic examination added little to clinical judgment when evaluating for sexually transmitted infections in young women.
Do Topical Antibiotics Help Conjunctivitis?
Topical antibiotic use for bacterial conjunctivitis was associated with improved rate of clinical cure compared to placebo. For early and late clinical cure with topical antibiotics, the NNT was 9 and 11, respectively.
Can We Risk Stratify Febrile Infants 29-60 Days?
The modified Philadelphia criteria had high enough sensitivity to rule out invasive bacterial infection in infants 29-60 days old without obtaining CSF. No infants 29-60 days old who were classified as low risk had bacterial meningitis.
Does Prednisone Help Post-herpetic Neuralgia?
Corticosteroids did not reduce the incidence of post-herpetic neuralgia at 6 months or pain severity at 3, 6, or 12 months. However, the evidence for this review was fairly weak. Two trials indicated that steroids may reduce short-term pain and speed healing at one month.