PRN dosing of antivenom (Crofab) for rattlesnake bite based on a clinical and laboratory-triggered strategy led to an overall decreased hospital length of stay (LOS) (27h vs 34h) and amount of antivenom used (8 vs 16 vials) compared to standard maintenance dosing.

Think of synthetic cannabinoid use in patients with unexplained serious coagulopathy due to possible contamination with long acting vitamin K antagonists. They will need prolonged oral vitamin K treatment, which can challenging due to the cost.

This single-center series found button batteries (BB) lodged in the esophagus all caused mucosal injury, but those in the stomach also caused mucosal injury in 6 out of 12.  We may need to rethink the urgency of retrieving gastric BB.

Capsaicin cream for cannabis hyperemesis has been described in adults; this is the first reported use in adolescent patients.  It appeared to help, N = 2.

Inadvertent poisoning with an opiate in the prehospital setting is unlikely, especially with routine personal protective equipment (gloves).

Hyperbaric oxygen therapy for carbon monoxide (CO) poisoning improved cognitive outcomes at 6 weeks and possibly at 12 months.

Crotalidae polyvalent immune antivenom (CroFab) improved limb disability in patients bitten by copperhead snakes.

Loperamide abuse is increasingly seen.  It can be rarely associated with cardiac conduction system disturbances.  Talk to poison control, and put these patients on a monitor.

Hyperbaric oxygen therapy for carbon monoxide poisoning decreased mortality, NNT = 10.

You really do need a 4-hour APAP level.  But if the <4 hour level is undetectable or "very low" you are in the clear.