Lowering glucose prior to discharge may negatively impact ED length of stay (LOS) without short-term benefit for the patient, but this study wasn’t able to prove it.
In patients with septic shock, those treated with hydrocortisone + fludrocortisone had a lower 90-day mortality compared to placebo (43% vs 49.1%, NNT 17). They also had significantly more vasopressor-free and organ-failure free days, in addition to having a shorter time to weaning from vasopressors and mechanical ventilation.
Discharge glucose level did not correlate with 7-day return to the ED. It looks like there isn't a specific target glucose we need to attain prior to discharge.