Tramadol Isn't Addictive, Right?

Tramadol Isn't Addictive, Right?

Use of tramadol post-op was associated with an increased risk of prolonged use compared with other short acting opiates.

Video on Hand and Wrist Exam - DeQuervain, Dupuytren, Durkan, Digitorum

Video on Hand and Wrist Exam - DeQuervain, Dupuytren, Durkan, Digitorum

Examining the hand and wrist is challenging. Watch this video on NEJM to learn proper techniques and how to diagnose 9 common hand/wrist problems.

Lemierre's Syndrome - Sore Throat Gone Wrong

Lemierre's Syndrome - Sore Throat Gone Wrong

Sometimes sore throat isn’t just sore throat - it could be a life threatening complication. Learn about Lemierre’s syndrome with this quick-hitter teaching case from NEJM.

Do Muscle Relaxers Help Back Pain?

Do Muscle Relaxers Help Back Pain?

There was no benefit in functional outcome or pain at one week by using ibuprofen + either baclofen, metaxolone, or tizanidine over ibuprofen + placebo.

What Defines Pediatric Hypotension?

What Defines Pediatric Hypotension?

The Pediatric Advanced Life Support (PALS)/Advanced Trauma Life Support (ATLS) formula to define hypotension in children (i.e. 5th percentile SBP) seems to be a good compromise between German and U.S. population norms for children. The formula is: Low SBP = <70 + 2(age in years).

Can We Use Ondansetron In Pregnancy?

Can We Use Ondansetron In Pregnancy?

In this large cohort study of over 1.8 million pregnancies, first trimester ondansetron use was not associated with cardiac malformations or total congenital malformations. However, there was a small increased risk of oral clefts (3 additional cases per 10,000 women treated).

Is This Patient Really Penicillin Allergic?

Is This Patient Really Penicillin Allergic?

Penicillin allergy is a lot less common than patients report. A low-risk history could allow you to prescribe it in the ED or clinic.

When Will Oral Antibiotics for Cellulitis Fail?

When Will Oral Antibiotics for Cellulitis Fail?

”Tachypnea at triage, chronic ulcers, history of MRSA colonization or infection, and cellulitis within the past year,” were the risk factors associated with failure of oral antibiotic therapy for non-purulent cellulitis.

Time to Take an Ax to the Wood's Lamp?

Time to Take an Ax to the Wood's Lamp?

The overall sensitivity of the Wood’s lamp, compared to the gold standard slit lamp, to establish the diagnosis of common corneal and conjunctival abnormalities was found to be an abysmal 52%.

Do Topical Antibiotics Help Conjunctivitis?

Do Topical Antibiotics Help Conjunctivitis?

Topical antibiotic use for bacterial conjunctivitis was associated with improved rate of clinical cure compared to placebo. For early and late clinical cure with topical antibiotics, the NNT was 9 and 11, respectively.

Do Probiotics Plus Antibiotics Prevent C. difficile?

Do Probiotics Plus Antibiotics Prevent C. difficile?

Probiotics decrease the risk of C. difficile infection in adults and children taking antibiotics and may reduce overall adverse events like cramping, nausea, or diarrhea.

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