Age-Adjusted D-dimer Cut-offs Reduce CT Use

Sharp AL, Vinson DR, Alamshaw F et al. An Age-Adjusted D-dimer Threshold for Emergency Department Patients With Suspected Pulmonary Embolus: Accuracy and Clinical Implications. Ann Emerg Med. 2015 Aug 27. pii: S0196-0644(15)00616-2. doi:10.1016/j.annemergmed.2015.07.026. [Epub ahead of print]

CONCLUSION: An age-adjusted D-dimer limit has the potential to reduce chest imaging among older ED patients and is more accurate than a standard threshold of 500 ng/dL. Our findings support the adoption of an age-adjusted D-dimer cutoff in community EDs. PMID: 26320520

Comment: Almost 3000 CT scans could have been averted, but 26 cases of PE would have been missed.  I am going to start using an age adjusted cut off (age x 10).  My grandpa could have a D-dimer of 930!

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