JournalFeed Landmark Articles

A few years ago, JournalFeed teamed up with Academic Life in EM to summarize the famous "52 in 52" landmark articles. As pivotal new research emerged, we kept going.

We have curated decades of medical knowledge into one essential, modern reference for you.

  • Living Document: Updated as new articles are released.
  • Hyperlinked: Active links to original sources.
  • Exclusive: Available to CORE, MAX, & PREMIUM members.
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JournalFeed Landmark Articles eBook

Why Landmark Articles?

Landmark articles are pivotal studies that transform clinical practice. They provide the highest-quality evidence, frequently cited in clinical guidelines, and set the standard of care we use every day.

From ischemic stroke to congestive heart failure and sepsis, these studies change how medicine is practiced worldwide.

Included Studies

  • Stroke (NINDS tPA): Established tPA as the first effective therapy for ischemic stroke.
  • Heart Failure (CRT): Proved cardiac resynchronization therapy reduces mortality.
  • Coronary Disease (CURE): Showed dual antiplatelet therapy outperforms aspirin alone.
  • Risk Factors (Framingham): Identified key cardiovascular risks still used in practice today.

Clinical Trials (RCTs)

The gold standard for testing new therapies. These are the studies that defined modern medicine.

Observational Studies

Providing long-term insights into disease progression and risk factors.

Surgical & Medical

Defining best practices in cancer treatment, cardiac care, and critical care surgery.