Toxicology

Can We Use Rivastigmine for the Treatment of Antimuscarinic Delirium?

Spoon Feed
In this small, retrospective review of 22 patients with antimuscarinic delirium who received antidotal therapy with transdermal +/- oral rivastigmine, there were no major adverse effects observed, and symptom resolution generally occurred within a matter of hours.

Source
Greene SC. Rivastigmine Use in the Treatment of Antimuscarinic Delirium. J Med Toxicol. 2023 Jul;19(3):284-287. doi: 10.1007/s13181-023-00947-1. Epub 2023 May 19.

Is It Just Me or Are We Seeing More Cannabis Hyperemesis?

Spoon Feed
Legalization of cannabis in Ontario was not associated with an increase in ED visits for cannabis hyperemesis syndrome (CHS); however, after legislation passed allowing commercialization of cannabis, there was a large increase in visits for CHS.

Source
Changes in Emergency Department Visits for Cannabis Hyperemesis Syndrome Following Recreational Cannabis Legalization and Subsequent Commercialization in Ontario, Canada. JAMA Netw Open. 2022 Sep 16. Doi:10.1001/jamanetworkopen.2022.31937

Scroll to Top