Comprehensive Venous Thromboembolism Articles

Cardiology Emergency Medicine Venous Thromboembolism

STORM-PE RCT—Thrombectomy for Intermediate-High Risk PE
January 9, 2026January 10, 2026

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This RCT of 100 patients with intermediate-high risk PE showed that mechanical thrombectomy plus anticoagulation was superior to anticoagulation alone in reducing RV/LV ratio and earlier normalization of vitals.

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STORM-PE Trial Investigators. Randomized Controlled Trial of Mechanical Thrombectomy With Anticoagulation Versus Anticoagulation Alone for Acute Intermediate-High Risk Pulmonary Embolism: Primary Outcomes from the STORM-PE Trial. Circulation. 2025 Nov 3. doi: 10.1161/CIRCULATIONAHA.125.077232. Epub ahead of print. PMID: 41183181.

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POCUS Venous Thromboembolism

New Video – How to POCUS PE
December 15, 2025December 23, 2025

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Watch the new video on how to use POCUS to find signs of pulmonary embolism (PE): septal bounce, D-sign, and McConnell sign. Plus, see a clot that’s about to shoot into the lung!

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The Need for SPEED: Sonography for Pulmonary Embolism in the Emergency Department. J Emerg Med. 2025 Nov;78:258-265. doi: 10.1016/j.jemermed.2025.03.017.

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POCUS Venous Thromboembolism

POCUS Improves PE Diagnosis and Treatment Times
December 8, 2025December 13, 2025

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In this single-center retrospective study, POCUS use was associated with a reduction in time to CT acquisition and anticoagulation delivery in patients with acute pulmonary embolism.

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The Need for SPEED: Sonography for Pulmonary Embolism in the Emergency Department. J Emerg Med. 2025 Nov;78:258-265. doi: 10.1016/j.jemermed.2025.03.017.

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Emergency Medicine OB/GYN Venous Thromboembolism

Latest Evidence to Diagnose and Manage PE in Pregnancy
November 6, 2025November 8, 2025

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This review outlines updated evidence and international guidelines for diagnosing and managing suspected pulmonary embolism (PE) in pregnancy.

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Diagnosing Pulmonary Embolism During Pregnancy. Chest. 2025 Oct;168(4):1007-1017. doi: 10.1016/j.chest.2025.05.014. Epub 2025 May 20. PMID: 40404047.

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Critical Care Emergency Medicine Ultrasound Venous Thromboembolism

STAMP Score Predicts Crashing in Intermediate-High Risk PE
October 7, 2025October 11, 2025

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The newly derived and validated STAMP score predicts clinical decompensation in patients with acute PE who are classified as intermediate-high risk per ESC guidelines.

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The STAMP score: An exploratory model for short-term risk stratification in intermediate-high-risk pulmonary embolism running head: The STAMP score. Eur J Intern Med. 2025 Aug 20:106484. doi: 10.1016/j.ejim.2025.106484. Epub ahead of print. PMID: 40841246.

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Family Medicine Hematology/Oncology Internal Medicine Venous Thromboembolism

Which DOAC Is Best for VTE?
June 26, 2025June 25, 2025

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Apixaban is associated with lower risks of recurrent VTE and major bleeding compared to rivaroxaban and warfarin.

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Oral Anticoagulation and Risk of Adverse Clinical Outcomes in Venous Thromboembolism. JAMA Intern Med. 2025 May 12:e251109. doi: 10.1001/jamainternmed.2025.1109. Epub ahead of print. PMID: 40354043

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Emergency Medicine POCUS Venous Thromboembolism

(D)on’t you want to (V)erify (T)hrombosis?
June 5, 2025June 1, 2025

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Proximal compression ultrasound (PUL) in the ED and risk stratification (via Well’s score) can result in appropriate evaluation and management decisions for patients presenting with concern for DVT.

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Proximal venous ultrasound with risk stratification safely excludes deep venous thrombosis in emergency department routine care: an observational study. Scand J Trauma Resusc Emerg Med. 2025 May 14;33(1):85. doi: 10.1186/s13049-025-01382-7. PMID: 40369661

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Family Medicine Hematology/Oncology Internal Medicine Venous Thromboembolism

Low-Dose Apixaban for Cancer-Associated VTE
May 20, 2025May 17, 2025

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For secondary prophylaxis of cancer-associated venous thromboembolism (VTE), reduced-dose apixaban is noninferior in terms of VTE recurrence and superior in terms of bleeding risk.

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Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism. N Engl J Med. 2025 Apr 10;392(14):1363-1373. doi: 10.1056/NEJMoa2416112. Epub 2025 Mar 29. PMID: 40162636

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POCUS Venous Thromboembolism

Can We Use AI for DVT POCUS?
May 5, 2025May 5, 2025

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AI guidance for DVT POCUS scan acquisition is effective and may have cost-saving potential.

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Value of clinical review for AI-guided deep vein thrombosis diagnosis with ultrasound imaging by non-expert operators. NPJ Digit Med. 2025 Mar 1;8(1):135. doi: 10.1038/s41746-025-01518-0. PMID: 40025255

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ED-Hospital-Clinic Operations Emergency Medicine Pediatric Emergency Venous Thromboembolism

Bringing PERT to Pediatrics
April 14, 2025April 13, 2025

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After starting a pulmonary embolism response team (PERT) at a large children’s hospital, all eligible cases of PE were activated, time to diagnosis and intervention decreased, and more patients received reperfusion, but length of stay and mortality was unchanged.

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Bringing PERT to Pediatrics: Initial Experience and Outcomes of a Pediatric Multidisciplinary Pulmonary Embolism Response Team (PERT). Chest. 2025 Mar;167(3):851-862. doi: 10.1016/j.chest.2024.09.028. Epub 2024 Oct 3. PMID: 39368735

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