Low-doses of IV epinephrine in unstable, hypotensive pediatric patients temporarily increased heart rate and mean arterial pressure.

There was no difference in 90-day mortality among critically ill, intubated patients with septic shock who received hydrocortisone 200mg IV daily and those who did not.  Shock resolved one day faster in the steroid group.

There was no advantage to giving IV acetaminophen for pain in the ED over oral.

Broad spectrum vs narrower spectrum antibiotics for routine pediatric respiratory infections were not more effective and were associated with an increased rate of complications.

Ketofol vs ketamine alone had the advantage of fewer unpleasant emergence reactions and less post-procedural vomiting.

Patients may still have opiate abuse or dependence even if they have no prescriptions recorded on a public controlled substance database.

Neither morphine+ibuprofen nor either drug alone+placebo improved pain to a minimal score at 1 hour in children with acute extremity pain.

A dose of ibuprofen 400mg + acetaminophen 1000mg was as good as an oral opiate for extremity pain.

Codeine prescriptions for children after tonsillectomy and adenoidectomy substantially dropped after the FDA issued a black box warning over safety concerns.  Still, 1 in 20 children continue to inappropriately receive codeine after T&A.

One of the most challenging things to memorize is what antibiotics cover what organisms.  This infographic can help.  If you can't view it, click this to see it online.  Please share with friends who may find it helpful.