Capsaicin cream for cannabis hyperemesis has been described in adults; this is the first reported use in adolescent patients.  It appeared to help, N = 2.

Young children with community acquired pneumonia seemed to do fine with a beta-lactam antibiotic only and didn't appear to benefit from adding a macrolide.

Not surprisingly, heavier patients had lower first-pass endotracheal tube success.  They also had succinylcholine under-dosed more often. Give yourself the best chance for success and optimize muscle relaxation in obese patients.

Naproxen + placebo was as good as (possibly better than) naproxen plus orphenadrine or naproxen plus methocarbamol for acute low back pain.

For patients on antiplatelet agents with epistaxis, tranexamic acid (TXA)-soaked pledgets were far more effective than lidocaine with epinephrine-soaked pledgets at stopping bleeding within 10 minutes and were better tolerated by patients.

After using ketamine for pediatric procedural sedation, 22% of children experienced negative behavioral symptoms measured 1-2 weeks after ED discharge. The most common symptoms were apathy/withdrawal and separation anxiety. Pre-procedural anxiety was the greatest predictor of negative behavioral changes.

Treatment with lytics for acute PE (mostly massive or with arrest) in pregnancy out to 6 weeks postpartum was associated with 94% overall maternal survival and 88% fetal survival.  Major bleeding occurred in 17% of pregnant women and 58% of those in the postpartum period.

Prophylactic ondansetron given with IV opiates did not decrease the rate of nausea or vomiting.

The primary outcome (quick and sustained headache relief) was achieved in 60% of the IV prochlorperazine + diphenhydramine group vs 31% in the IV hydromorphone group with a NNT of 4. As a result, the study was stopped early.

Morphine was associated with worse short-term mortality all other known variables being equal: 20% vs. 12.7%.