January 2024
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Jan 17 2024
Do Febrile Neonates with COVID-19 Need a Full Workup?
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This systematic review and meta-analysis of almost 4,000 febrile infants ≤ 90 days old diagnosed with COVID-19 indicated that these patients have a low prevalence of invasive bacterial infection (IBI), especially the subgroup >28 days old. -
Jan 16 2024
Oxy-PICU RCT – Oxygenation Targets in Ventilated Children
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A conservative (SpO2 88-92%) oxygenation target resulted in a small but significant greater probability of better outcome compared to a liberal (SpO2 >94%) target in children admitted to the PICU on invasive mechanical ventilation.Source
Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial. Lancet. 2023 Dec 1:S0140-6736(23)01968-2. doi: 10.1016/S0140-6736(23)01968-2. Epub ahead of print. -
Jan 15 2024
Can We Seriously Consider Non-op Management of Appendicitis?
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This expert opinion piece recommends consideration of nonoperative antibiotic treatment for select cases of uncomplicated acute appendicitis.Source
Treatment of Acute Uncomplicated Appendicitis. Treatment of Acute Uncomplicated Appendicitis. N Engl J Med. 2021 Sep 16;385(12):1116-1123. doi: 10.1056/NEJMcp2107675. -
Jan 12 2024
REBOA or Thoracotomy – Which Is Better?
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Traumatic cardiac arrest patients receiving either resuscitative endovascular balloon occlusion of the aorta (REBOA) or resuscitative thoracotomy (RT) experienced similar outcomes, though time to successful occlusion of the aorta took significantly longer with REBOA. The limiter? Common femoral artery (CFA) access.Source
Resuscitative endovascular balloon occlusion of the aorta and resuscitative thoracotomy are associated with similar outcomes in traumatic cardiac arrest. J Trauma Acute Care Surg. 2023 Dec 1;95(6):912-917. doi: 10.1097/TA.0000000000004094. Epub 2023 Jun 29. -
Jan 11 2024
Can Topical Lidocaine Help Solve Chronic Neck Pain?
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In this randomized trial of patients with chronic neck pain, patients who received lidocaine patch treatments had an equivalent pain response to patients who received placebo patches.Source
Multicenter, Randomized, Placebo-Controlled Crossover Trial Evaluating Topical Lidocaine for Mechanical Cervical Pain. Anesthesiology. Published online December 11, 2023. doi:10.1097/ALN.0000000000004857. -
Jan 10 2024
High-Dose Nitroglycerin for SCAPE – But How High?
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High-dose nitroglycerin improves outcomes in patients with sympathetic crashing acute pulmonary edema (SCAPE) without significant side effects when compared to low-dose nitroglycerin. -
Jan 09 2024
TENSION RCT – Thrombectomy for Large-Infarct Volume Strokes
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Endovascular thrombectomy plus medical care is better than medical care for patients with large vessel occlusion (LVO), even with established large infarcts.Source
Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial. Lancet. 2023 Nov 11;402(10414):1753-1763. doi: 10.1016/S0140-6736(23)02032-9. Epub 2023 Oct 11. PMID: 37837989. -
Jan 08 2024
Best POCUS Papers Made Easy? Count Me In!
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This expert panel from Canada has compiled a list of what they deem to be the most influential POCUS papers with regard to cardiac arrest as well as evaluation of shock. Whether you want to further educate yourself or guide your residents to learn more on the subject, this primer is a great place to start.Source
POCUS literature primer: key papers on POCUS in cardiac arrest and shock. CJEM. 2023 Nov 23. doi: 10.1007/s43678-023-00611-1. Epub ahead of print. -
Jan 05 2024
Sodium Bicarb Increases End-Tidal CO2 Values
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A prospective, observational study demonstrated that giving sodium bicarbonate to patients undergoing mechanical ventilation or CPR resulted in an increase in end-tidal CO2 values in as quickly as 17 seconds and lasted for 7 minutes.Source
End-tidal carbon dioxide after sodium bicarbonate infusion during mechanical ventilation or ongoing cardiopulmonary resuscitation. Am J Emerg Med. 2023 Nov 25:76:211-216. doi: 10.1016/j.ajem.2023.11.027. Online ahead of print. -
Jan 04 2024
New – 2023 AHA ACLS Updates
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In this focused update to the AHA Guidelines for Cardiopulmonary Resuscitation (last updated 2020), the study group recommended against routine use of calcium in cardiac arrest while recommending for a targeted temperature control strategy in patients who do not follow commands post ROSC, among other recommendations.Source
American Heart Association. 2023 American Heart Association Focused Update on Adult Advanced Cardiovascular Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2023 Dec 18. doi: 10.1161/CIR.0000000000001194. Epub ahead of print.