Aug 06 2020
Brain Clot Score – Cerebral Venous Thrombosis Rule
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A new scoring system was developed fo cerebral venous thrombosis (CVT). It is not ready for implementation until externally validated, but it was encouraging that none with a score of 0-2 and D-dimer <500 had CVT.
Jul 09 2020
Get Smart on CAR-T – Spoon Feed Version
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We need to know about the adverse effects of CAR-T therapy - how to recognize and treat it emergently. Here is your guide.
Jul 01 2020
HALT-IT – TXA for GI Bleed
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TXA did not reduce mortality within 5 days in patients with upper and lower GI bleeding, but it did increase risk of venous thromboembolism.
Jun 22 2020
Is Vitamin K Needed for INR Over 10?
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In asymptomatic patients with INR>10, vitamin K administration was not associated with improved clinical outcomes.
Jun 03 2020
TXA in the Real World – More Thromboembolic Events?
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TXA administration for trauma patients in a U.S. level 1 trauma center was associated with similar overall mortality but greater risk for thromboembolic events than the original CRASH-2 cohort.
May 15 2020
Should We Rethink Pregnancy-Adapted YEARS Criteria?
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Had the pregnancy-adapted YEARS algorithm been applied in the DiPEP population, it would have missed a significant number of PEs. But there are several limitations to this study.
Apr 21 2020
Who Needs CT? Aspirin, Clopidogrel, Warfarin, or a Combination?
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Patients taking warfarin or dual aspirin/clopidogrel therapy were at greater risk for significant intracranial injury on CT. Scan these folks.
Mar 17 2020
Emergency Guide to Novel Cancer Treatments
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Dozens of new therapies for hematologic malignancies have been added over the past few years. This summary is the bare minimum you must know to care for these patients.
Jan 30 2020
Is It Time to Adjust D-dimer Thresholds to Our Clinical Pretest Probability?
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style="white-space:pre-wrap;">Using the Wells Score to categorize patients as low, moderate or high clinical pretest probability in conjunction with adjusted positive D-dimer thresholds at >1000 ng/mL for a low or >500 ng/mL for a moderate Wells Score, the authors reduced diagnostic chest imaging in the ED with no incidence of missed venous thromboembolism at 90 days.
Jan 03 2020
IV TXA for Hemoptysis
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style="white-space:pre-wrap;">Intravenous tranexamic acid may reduce in-hospital mortality, length of stay, and total healthcare costs for patients admitted with hemoptysis.