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Proton pump inhibitor (PPI) use in young children is associated with risk of serious infection. It’s best to avoid PPI use in the absence of a very clear indication.
Source
Proton Pump Inhibitor Use and Risk of Serious Infections in Young Children. JAMA Pediatr. 2023 Aug 14;e232900. doi: 10.1001/jamapediatrics.2023.2900. Online ahead of print.
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Is taking a croupy child outdoors in the cold air an old wive’s tale or evidence-based practice? Turns out, it actually works!
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Structured surveillance without anticoagulation of patients with isolated subsegmental pulmonary embolism (ssPE) rarely occurs in community practice. After applying CHEST guidelines, ~5% of patients with isolated subsegmental PE are eligible for surveillance.
Source
Prevalence of and Eligibility for Surveillance Without Anticoagulation Among Adults With Lower-Risk Acute Subsegmental Pulmonary Embolism. JAMA Netw Open. 2023;6(8):e2326898. Published 2023 Aug 1. doi:10.1001/jamanetworkopen.2023.26898
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Through education and advocacy, we can reduce the risk of global nuclear conflict. You have more power to change the world than you might think.
Source
Reducing the Risks of Nuclear War-The Role of Health Professionals. JAMA. 2023 Aug 15;330(7):601-602. doi: 10.1001/jama.2023.14519.
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ACEP has issued an updated Clinical Policy to provide evidence-based guidelines for management of adult patients presenting to the ED with mild traumatic brain injury based on systematic review of available literature.
Source
Clinical Policy: Critical Issues in Management of Adult Patients Presenting to the Emergency Department with Mild Traumatic Brain Injury. Ann Emerg Med. 2023 May; 81(5): e63-e105. doi: 10.1016/j.annemergmed.2023.01.014.
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This article was a multi-institutional prospective validation of the American Association for Surgery of Trauma (AAST) Brain Injury Guidelines (BIG), which were developed to guide effective resource utilization for traumatic brain injury. The validation study demonstrated that this system was accurate and safe and that its implementation can reduce CT scan utilization and neurosurgical consultation.
Source
Validating the Brain Injury Guidelines: Results of an American Association for the Surgery of Trauma prospective multi-institutional trial. J Trauma Acute Care Surg. 2022 Aug 1;93(2):157-165. doi: 10.1097/TA.0000000000003554. Epub 2022 Mar 28.
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Direct oral anticoagulants (DOACs) are safe and effective for the treatment of pulmonary embolism (PE).
Written by Alex Clark Spoon FeedIn minor acute ischemic stroke (AIS) patients presenting within 4.5 hours of onset, dual antiplatelet therapy (DAPT) is non-inferior to intravenous alteplase for excellent neurologic outcome at 90 days. Let me get this straight… DAPT is not, not, not worse than tPA?Current guidelines recommend thrombolytics for AIS patients presenting within …
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There is no association between the weight-based drug dose of etomidate or ketamine and post-intubation hypotension.
Source
Sedative Dose for Rapid Sequence Intubation and Postintubation Hypotension: Is There an Association? Ann Emerg Med. 2023 Jun 30;S0196-0644(23)00379-7. doi: 10.1016/j.annemergmed.2023.05.014. Online ahead of print.
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At least in the initial period, there appears to be no clinically meaningful difference in IQ scores in pediatric patients after a concussion.
Source
IQ After Pediatric Concussion. Pediatrics. 2023. 152(2);e2022060515. https://doi.org/10.1542/peds.2022-060515.
