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Point-of-care ultrasound (POCUS) should be utilized in conjunction with the history and physical exam for the differentiation of cellulitis versus abscess.
Source
What is the Utility of Point-of-Care Ultrasound for Diagnosis of Soft Tissue Abscess vs. Cellulitis? J Emerg Med. 2025 May;72:121-128. doi: 10.1016/j.jemermed.2024.11.012. Epub 2024 Nov 26. PMID: 40274497
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Dazukibart is a neutralizing monoclonal antibody against interferon-β (IFNβ) which shows effectiveness and safety for patients with moderate-to-severe, treatment-refractory cutaneous dermatomyositis.
Source
Efficacy, safety, and target engagement of dazukibart, an IFNβ specific monoclonal antibody, in adults with dermatomyositis: a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial. Lancet. 2025 Jan 11;405(10473):137-146. doi: 10.1016/S0140-6736(24)02071-3. PMID: 39798982
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The AAAAI/ACAAI Joint Task Force released updated guidelines for the treatment of pediatric atopic dermatitis (AD). Medications are just one aspect and must be accompanied by ongoing patient education, trigger avoidance, and frequent moisturizing.
Source
Updated Guidelines for Atopic Dermatitis-AAAAI/ACAAI Joint Task Force. JAMA Pediatr. 2024 Oct 1;178(10):961-962. doi: 10.1001/jamapediatrics.2024.1395. PMID: 38976275
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In a cohort of afebrile infants with pustular or vesicular rashes, none were diagnosed with serious bacterial infection attributable to a skin source, though some were ultimately diagnosed with herpes simplex virus (HSV).
Source
Management of Pustules and Vesicles in Afebrile Infants ≤60 Days Evaluated by Dermatology. Pediatrics. 2024 Jul 1;154(1):e2023064364. doi: 10.1542/peds.2023-064364. PMID: 38910522.
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This article reviews the literature regarding drug reaction with eosinophilia and systemic symptoms (DRESS) and focuses on the EM and critical care physician’s perspective, summarizing the presentation, clinical features, and management.
Source
Drug reaction with eosinophilia and systemic symptoms: An emergency medicine focused review. Am J Emerg Med. 2022 Jun;56:1-6. doi: 10.1016/j.ajem.2022.03.024. Epub 2022 Mar 18.
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Point-of-care ultrasound (POCUS) was accurate in distinguishing cellulitis from abscess.
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If you accidentally glue someone’s eye shut, soaking the eye in dexamethasone, polymyxin B, neomycin antibiotic drops was most effective at loosening histoacryl tissue adhesive.
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Treating non-purulent cellulitis with narrow spectrum antibiotics improves meaningful patient outcomes. Stop throwing vancomycin around or adding TMP/SMX to cephalexin if there is no pus. See this algorithm.
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Point of care ultrasound was accurate for diagnosis of skin abscess, but the results of this review may have been inflated. It is likely most helpful in uncertain cases.
Simply providing cool running water for 20 minutes within 3 hours of injury for children with burns was associated with a marked reduction in need for skin grafting and possibly burn depth and need for hospitalization.