Muscle Relaxers Add Nothing to Naproxen for Back Pain
Naproxen + placebo was as good as (possibly better than) naproxen plus orphenadrine or naproxen plus methocarbamol for acute low back pain.
TXA for Epistaxis
For patients on antiplatelet agents with epistaxis, tranexamic acid (TXA)-soaked pledgets were far more effective than lidocaine with epinephrine-soaked pledgets at stopping bleeding within 10 minutes and were better tolerated by patients.
Is There Such Thing as a Black Cloud?
There is no such thing as a "black cloud." Those who self-identified as a black-cloud were also identified as such by their peers, but a look at the actual PED metrics showed no statistical difference except higher admission rate. I'm not sure I believe this, but there you go...
No Cruising? No Bruising – Outcome of Bruising in Premobile Infants
Bruising in premobile children means trouble. The most important take home is: "More than half of premobile infants with initially unexplained bruises were found to be abused." Bruising before they're cruising needs a workup and DCS referral.
Ultrasound For Abscess in Children – The MRSA Era
Sonographically occult perineal abscess in children was surprisingly common, 28% (61/217). More than half had I&D within 4 hours of a "negative" radiology-obtained ultrasound. Symptoms < 4 days, age < 4 years, and history of MRSA were all associated with false negative ultrasound.
Ketamine and Long-term Behavioral Change in Children
After using ketamine for pediatric procedural sedation, 22% of children experienced negative behavioral symptoms measured 1-2 weeks after ED discharge. The most common symptoms were apathy/withdrawal and separation anxiety. Pre-procedural anxiety was the greatest predictor of negative behavioral changes.
Myth Bust – Ondansetron and IV Opiate-Induced Nausea
Prophylactic ondansetron given with IV opiates did not decrease the rate of nausea or vomiting.
IV Prochlorperazine + Diphenhydramine vs Hydromorphone for Migraines
The primary outcome (quick and sustained headache relief) was achieved in 60% of the IV prochlorperazine + diphenhydramine group vs 31% in the IV hydromorphone group with a NNT of 4. As a result, the study was stopped early.
Canadian C-spine Rule for Clinical Clearance
The Canadian C-spine rule has high sensitivity for c-spine injury and higher specificity than the NEXUS rule. It allows clinical clearance of more people.
She’s My Surgeon – Female vs. Male Surgical Outcomes
Female surgeons had small but significantly improved 30-day mortality and other surgical outcomes over male surgeons, all other factors being equal.