Are Bullet Fragments Causing Lead Poisoning?
Patients with retained bullet fragments are at risk for toxic lead levels and should probably be screened for the first year after ballistic injury.
Cannabis Legalization – Point | Counterpoint
We need to understand arguments for and against full legalization of cannabis for recreational purposes. This has not only public health implications but has direct impact on the ED, with increased volume, trauma, and burden of psychiatric illness.
Cannabis In Colorado – A Cautionary Tale
Cannabis has some medical benefit, but there are some adverse health consequences worth reviewing as additional states consider legalization in the U.S.
Heroin OD With Naloxone – Is 2h Observation Enough?
In heroin users specifically, 5% needed either repeat naloxone or oxygen > 2 hours after initial naloxone reversal. Observation for 3 hours may be safer, especially for those with polysubstance abuse.
Black Widow Antivenin – Does It Work?
Purified black widow spider antivenin was more effective for pain control than placebo and not associated with any adverse drug effects.
NACSTOP – Safety of a 12-hour NAC Protocol
A 250mg/kg, 12-hour N-acetylcysteine (NAC) protocol was as effective as the usual 300mg/kg, 20-hour protocol in patients at lower risk for hepatotoxicity.
Nerve Agent Incidents and Public Health Preparedness
Management of nerve agent (NA) poisoning requires recognition of the syndrome and availability of the antidote. It is important to remember that besides the classic “SLUDGE” and “Killer B’s,” there is also the nicotinic syndrome which can cloud the clinical presentation. Add the “weekdays” mnemonic for nicotinic effects to your list of symptoms in NA toxicity.
Tox Myth-Bust – Prehospital Exposure to Fentanyl Analogs
Alex Chen goes in depth with this toxicology myth-bust on the risk of exposure to fentanyl or fentanyl analogs to prehospital personnel.
HOUR – Early Discharge After Opioid OD
The HOUR clinical decision rule can help determine which patients with opioid overdose who have received prehospital naloxone are safe for discharge after one hour of observation. But clinician judgment was just as good, which begs the question of why we need a decision rule.
Predicting Severe Alcohol Withdrawal
Individual risk factors associated with the development of severe alcohol withdrawal syndrome (SAWS) included a history of delirium tremens and baseline BP ≥ 140mmHg but no individual symptoms or signs associated with exclusion of SAWS. Composite measures fared better, such as the Prediction of Alcohol Withdrawal Severity Scale; a score ≥ 4 had a LR of 174 (95% CI 43-696).