MENDS2 – Dexmedetomidine vs Propofol – Which Is Better?
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For light sedation in patients with sepsis on the ventilator, there was no difference in outcome or safety between dexmedetomidine and propofol.
March 2021
REALITY RCT – PRBC Transfusion in Acute MI
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A restrictive vs liberal transfusion strategy in patients with acute MI was non-inferior when considering 30-day MACE.
Does FAST Exam Help in Pediatric Trauma?
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A positive FAST exam in hemodynamically stable children with blunt abdominal trauma warrants CT; a negative FAST should not be falsely reassuring that intraabdominal injury is absent.
New Nerve Block for Renal Colic?
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Consider the erector spinae plane block to reduce NSAID and opioid use in patients with renal colic.
PARAMEDIC2 – Epinephrine vs Placebo OHCA 6-12 Months
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More patients in PARAMEDIC2 who received epinephrine vs placebo survived for 6 or 12 months, but epinephrine did not improve favorable neurological outcome, mirroring the 30-day results of the original trial.
Acute Pancreatitis – Spoon-Feed Version
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Acute pancreatitis is a common ED complaint. This will help you manage it well.
GCS 8 – Intubate…Right?
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Patients with isolated head trauma and GCS 7 or 8 had greater odds of mortality when intubated immediately. But this is not the study to override the GCS 8 = intubate dogma.
How to Manage Pediatric UTI – Spoon-Feed Version
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Appropriate diagnosis of urinary tract infection (UTI) in children is important, as missed UTI can lead to renal scarring and other complications while over-diagnosis promotes antibiotic resistance.
Cherry Picking Patients – Resident Self-Assignment Pitfalls
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Resident characteristics, in particular gender and training specialty, were shown in this study to be associated with preferential patient self-assignment. Male residents were less likely to see breast-related chief complaints or vaginal bleeding. Off-service residents were more likely to see familiar chief complaints (e.g. surgery residents signing up for lacerations).
Prehospital TXA for Trauma – Meta-analysis
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When given by prehospital providers for suspected significant hemorrhage, TXA reduces 24-hour mortality but doesn’t affect 28-30-day mortality.