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Ludwig’s angina is a life-threatening infection of the floor of the mouth and requires prompt clinical recognition, airway evaluation, and treatment with broad-spectrum antibiotics and surgical source control.
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Prevalence of pulmonary embolism (PE) was about 6% in this prospective trial looking at patients admitted to the hospital with worsening respiratory symptoms in the setting of known COPD.
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In patients with abnormal vitals and suspicion for pulmonary embolism (PE), focused cardiac ultrasound (FOCUS) is highly sensitive (92%), especially for those with a heart rate >110BPM (approaching 100%).
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In patients given pain dose IV sub-dissociative ketamine, a lower dose (0.15mg/kg) was non-inferior to a higher dose (0.30mg/kg) for pain relief at 30 minutes and had fewer adverse effects.
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Low PEEP in mechanically ventilated patients without ARDS was noninferior to high PEEP for number of ventilator-free days.
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ECG abnormalities seen in patients with COVID-19 are likely due to a combination of factors. Abnormalities most commonly include supraventricular tachycardias, specifically sinus tachycardia.
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ULTRA-early, short term IV TXA in patients with SAH with suspected aneurysm rupture did not improve clinical outcomes of patients as described by “good” (0-3) versus “poor” (4-6) modified Rankin Scale at 6 months.
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In patients with acute traumatic brain injury, tranexamic acid did not improve mortality or neurological outcome among survivors.
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When septic patients with persistent tachycardia after initial resuscitation received ultra-short acting β-blockers, 28-day mortality was significantly lower, NNT 5.5.
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Epinephrine for cardiac arrest improves ROSC and survival but may only benefit long-term neurologically intact outcomes when given early in patients with non-shockable rhythms.
