Fluoroquinolones and Aortic Dissection – Again
Use of fluoroquinolones was associated with a 2.5-fold increase in risk of hospitalization for aortic aneurysm or aortic dissection.
Epi vs. Norepi for Cardiogenic Shock
Among patients with cardiogenic shock secondary to acute myocardial infarction (AMI), epinephrine led to a significantly increased rate of refractory shock compared to norepinephrine.
Nasal Spray Calcium Channel Blocker for SVT
Nasally administered etripamil was more effective than placebo at converting SVT to normal sinus rhythm and is now moving on to phase 3 trials. Stay tuned.
High-Sensitivity Troponin Rapid Rule-Out Protocol in the U.S.
Use of a rapid rule-out MI protocol with hs-cTnT was safe, accurate, and would have reduced time to discharge and increased the proportion of patients ruled out in this U.S.-based implementation study.
Stuff the Cuff – Home BP Cuffs Don’t Help
Self-referral for elevated blood pressure after using a home or pharmacy cuff had a very low admission rate at 3%.
Are We Underdosing Aspirin?
A low daily dose of aspirin (75-100mg) prevents cardiovascular events only in patients weighing < 70 kg. Higher doses are required in patients weighing more.
LOWMAGHI – Magnesium for Afib Rate Control
Among patients with atrial fibrillation with rapid ventricular response, low-dose magnesium (4.5g over 30 minutes) is an effective adjunct to standard therapy compared to placebo and causes far fewer side effects than high dose magnesium.
Does Negative CTPA Rule Out High Pretest Probability PE?
For patients with high pretest probability for pulmonary embolism, a negative CT pulmonary angiography alone does not appear to adequately rule out venous thromboembolism.
Infective Endocarditis – Spoon Feed
JAMA recently covered infective endocarditis (IE). I thought the JF readers would be well served by a Spoon Feed version. This thing is 12 pages long with 117 references. Let's miniaturize it, shall we?
Can We Use Beta-Blockers With COPD?
Patients with cardiovascular disease and concomitant COPD can be safely treated with a combination long-acting beta-agonist and a long-acting muscarinic antagonist when on a baseline beta-blocker.