JournalFeed week in review - was it a POCUS hate train this week? Maybe not…

Tachypnea, chronic ulcers, prior MRSA colonization, and prior cellulitis in the past 12 months were all associated with an increased risk of oral antibiotic failure for treatment of non-purulent cellulitis.

Nitrofurantoin was clearly superior to fosfomycin for uncomplicated UTI in adult women.

Lumbar puncture (LP) is low yield in children with complex febrile seizure (CFS).  Use caution if unvaccinated or pretreated with antibiotics.

Influenza killed 675 children from the 2010-11 flu season to the 2015-16 season.  Infants under 6 months had the highest incidence of mortality.  Encourage everyone to get vaccinated.  Antiviral treatment is encouraged in all children under 2, all patients with severe illness, and all hospitalized patients regardless of whether or not the duration of illness exceeds 48 hours.

The Surviving Sepsis Campaign has issued a new 1-hour bundle beginning at the time of triage in the emergency department. This replaces the current 3- and 6-hour bundles.

Blood cultures were low yield in patients admitted with cellulitis, and should largely be avoided.  Similarly, imaging was also low yield but changed management in a minority of cases.

Fluoroquinolone use was associated with increased risk of developing newly diagnosed aortic aneurysm or dissection.

This meta-analysis of 4 RCTs found anti-MRSA antibiotics in addition to I&D led to a far better cure rate than I&D alone.

If you're still reaching for metronidazole in patients with suspected or confirmed C. difficile colitis, it's time to get up to speed with this summary.