Vaping has been associated with severe acute lung injury in over 500 young people, and seven have died to date. Here is what you need to know.

Procalcitonin is not sufficiently accurate for ruling in or out bacterial pneumonia.

Overall yield of blood culture for pediatric community acquired pneumonia (CAP) was low; 91 blood cultures were needed to get one positive result. But in children admitted to the ICU, one child had bacteremia for every 24 cultures obtained; one for every 12 in children with parapneumonic effusion.

The CDC no longer recommends* annual TB screening of health care providers in the absence of a known exposure or ongoing transmission.

Early use of a paralytic infusion with deeper sedation did not reduce 90-day mortality in patients with ARDS compared to patients managed with lighter sedation and no paralytics.

Presence of any virus on multiplex PCR (particularly influenza, parainfluenza, and RSV) in critically ill hematology patients was associated with an increased risk for respiratory failure and ICU mortality.

Providing bag-mask ventilation (BMV) during the apneic phase of RSI improved oxygenation compared to standard RSI and did not increase the rate of complications.

In patients with acute respiratory distress, but not ARDS, a low tidal volume (VT) vs intermediate VT strategy did not reduce ventilator-free days or other outcomes, such as 28 or 90-day mortality.

High flow nasal cannula did not reduce 28-mortality in immunocompromised patients with acute hypoxemic respiratory failure compared to standard oxygen therapy.

Out of 83 patients with severe anaphylaxis, 1 had a probable biphasic allergic reaction, which was mild and consisted of rash only. No patients developed true biphasic anaphylaxis.