In pre-hospital management of anaphylaxis, co-treatment with both epinephrine and antihistamines may reduce the risk of uncontrolled reactions, while use of prehospital corticosteroids may increase rates of admission.

There was no difference in ventilator-free days in mechanically ventilated ICU patients when the SpO2 range was 90 to 97% vs 90% to no upper limit.

The ideal range of SpO2 associated with the lowest mortality in critically ill patients in this large, retrospective study was 94-98%.

Reduce blood cultures, ditch procalcitonin, reduce anaerobic coverage for aspiration, no more empiric corticosteroids, no more HCAP and knee jerk broad spectrum antibiotics - these are some of the updates since 2007. Read more.

High-dose vitamin C made no impact on short-term SOFA score or in lowering inflammatory markers in patients with sepsis and ARDS. There may have been a 28-day mortality reduction in the vitamin C group.

Focused cardiac ultrasound (FOCUS) is sensitive for detecting the presence of PE in those with a HR > 100bpm or systolic blood pressure <90 and highly sensitive for detection of PE in patients with a HR  > 110bpm.

Hyperoxemia was associated with increased odds of ICU mortality but lacked a dose-response. This is more evidence that favors targeting SpO2 targets around 97% instead of 100%.

Massive hemoptysis is a life-threatening emergency. Here are the top ten tips to give our patients the best shot at survival.