For patients with hemoptysis, inhaled tranexamic acid was associated with significantly reduced expectorated blood volume, hospital length of stay, need for invasive interventions, and hemoptysis recurrence rate at one year.

Adults with cough <3weeks or 3-8 weeks with post-tussive vomiting or whooping should be treated for pertussis; those with fever or without paroxysmal cough should be considered to have an alternate diagnosis. Children with <4 weeks of cough and post-tussive vomiting may have pertussis, but it was much less clear than in adults.

Specific emergency department variables are strongly predictive of infants with bronchiolitis requiring escalated care.

Simplified PESI (sPESI) and Hestia scores identified similar numbers of patients with pulmonary embolism as low risk. Both groups had similar 30-day all-cause mortality. However, interobserver reliability was better with sPESI.

CURB-65 was a poor predictor of the need for critical care intervention in adult patients with community acquired pneumonia.

For patients with high pretest probability for pulmonary embolism, a negative CT pulmonary angiography alone does not appear to adequately rule out venous thromboembolism.

Patients with cardiovascular disease and concomitant COPD can be safely treated with a combination long-acting beta-agonist and a long-acting muscarinic antagonist when on a baseline beta-blocker.

For adults with varied acute illnesses, use of supplemental oxygen in patients with room air SpO2 of 94% or greater was associated with increased short and longterm mortality.

ACEP has taken a stand on some of the most contemporary issues within the diagnosis and management of venous thromboembolic disease in the emergency department.

High-flow nasal cannula (HFNC) helped reduce treatment failure compared to standard nasal cannula in infants under 12 months with bronchiolitis requiring supplemental oxygen, NNT = 9.