The incidence of frostbite is shifting from exploration to urban environments and requires prompt recognition and often presents with other disease processes. Standard treatment is supportive and conservative, but new therapies including direct and systemic thrombolysis, and anticoagulation may be the future.
Diagnosis and Treatment of Frostbite. NEJM. 2022;386(26):2213-2220. Doi:10.1056/NEJMra1800868