Flamin’ Hot Elbows – Should We Aspirate Olecranon Bursitis?
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Empiric antibiotics, without aspiration, is safe and effective for most cases of suspected septic olecranon bursitis.
January 2022
The Ideal PE Rule-Out? RCT – PERC+YEARS+Age-Adjusted D-Dimer
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In PERC positive patients, use of YEARS with age-adjusted D-dimer was noninferior to an age-adjusted D-dimer strategy alone.
HEP-COVID RCT -Full Dose Anticoagulation for COVID-19?
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In adult COVID-19 patients with high thrombosis risk, empiric therapeutic dose enoxaparin reduced a composite outcome incidence of thrombotic events or 30-day all-cause mortality relative to prophylactic regimens with no significant difference in major bleeding. The difference was driven by a reduction in venous thromboembolism (VTE) and was not observed in ICU patients.
Update on Antithrombotic Therapy for VTE Disease
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We dig into the new VTE update on antithrombotic therapy in this post.
Prediction of Early Major Bleeding in Acute PE
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A new risk score (PE-SARD) stratifies patients with acute pulmonary embolism (PE) to predict early, major bleeding events.
EvK Trial – Etomidate vs Ketamine for RSI
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In this single-center RCT, 7-day survival was lower with etomidate than ketamine, 77.3% vs 85.1%.
No LP if CT Negative Out to 24 Hours?
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When using multislice CT (MSCT) scanners this study suggests it may be possible to extend the timeframe from headache onset within which aneurysmal subarachnoid hemorrhage (aSAH) can be effectively ruled out with imaging alone. They found that when MSCT was employed within 24 hours of symptom onset, the sensitivity of detecting aSAH remained 100%.
New PE-SCORE – Predicting Near-Term PE Outcomes
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The PE-SCORE has been derived and validated to determine which patients with PE are at risk of clinical deterioration or death. Patients with a score of 0 had an 8% chance of deterioration but no death; scores ≥6 all had deterioration or death.
CODA RCT | Pills or Knife for Appendicitis – Long-Term Outcomes
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The CODA trial initially found antibiotic treatment was noninferior to surgery for acute appendicitis at 30 days. In this follow up letter on long-term outcomes (up to 4 years), the incidence of appendectomy in the antibiotic group was higher than pooled results from prior trials.
High-Flow vs. Conventional Oxygen for Severe COVID-19
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Patients suffering from severe COVID-19 who are treated with high-flow oxygen nasal cannula, compared with those treated with conventional supplemental oxygen, have decreased need for mechanical ventilation and more rapid clinical recovery.