Month: January 2022

HEP-COVID RCT -Full Dose Anticoagulation for COVID-19?

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In adult COVID-19 patients with high thrombosis risk, empiric therapeutic dose enoxaparin reduced a composite outcome incidence of thrombotic events or 30-day all-cause mortality relative to prophylactic regimens with no significant difference in major bleeding. The difference was driven by a reduction in venous thromboembolism (VTE) and was not observed in ICU patients.

No LP if CT Negative Out to 24 Hours?

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When using multislice CT (MSCT) scanners this study suggests it may be possible to extend the timeframe from headache onset within which aneurysmal subarachnoid hemorrhage (aSAH) can be effectively ruled out with imaging alone. They found that when MSCT was employed within 24 hours of symptom onset, the sensitivity of detecting aSAH remained 100%.

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