Meningitis was a very rare cause of status epilepticus (SE) in this retrospective single-center review.
Month: August 2017
Idarucizumab reverses anticoagulation 100% due to dabigatran in the test tube. It seemed to stop active bleeding in patients in about 2.5 hours, and reported operative hemostasis was good. But since this was an open label trial with no control group, we don’t know how the outcomes would have compared with patients who were treated with other procoagulants or who were not treated.
If clinical gestalt for PE is low, use PERC to rule out PE. If not ruled out, use a validated tool to determine pretest probability of PE: Wells, Revised Geneva, or simplified versions of either score. If non-high or “unlikely” pretest probability, order D-dimer, adjusting for age (<500 or <age x 10). If D-dimer is negative, PE is ruled out. If positive, order CT pulmonary angiogram.
A negative c-spine CT had 99.9% NPV for clinically significant c-spine injury in intoxicated patients. The Western Trauma Association recommends c-spine clearance, even in intoxicated patients, if gross motor function is normal, no neurologic complaints, and negative c-spine CT per experienced radiologist. Be careful out there, and get institutional buy-in if you plan to put this into practice.