In patients admitted to the hospital with concern for ACS and discharged without a specific diagnosis, the higher the troponin elevation above the 99th percentile, the greater their risk for major adverse events.
In this large cohort study of over 1.8 million pregnancies, first trimester ondansetron use was not associated with cardiac malformations or total congenital malformations. However, there was a small increased risk of oral clefts (3 additional cases per 10,000 women treated).
The prevalence of traumatic brain injury (TBI) on CT in children with head injury presenting > 24 hours post-injury was 3.8%. Predictors on TBI on CT were suspicion of depressed skull fracture and non-frontal scalp hematoma.
Treating skin and soft tissue abscesses with antibiotics in addition to incision and drainage (I&D) resulted in significantly increased clinical cure rate (NNT = 14) and decreased incidence of new lesions (NNT = 10) compared to I&D alone.