Is It Time to Adjust D-dimer Thresholds to Our Clinical Pretest Probability?
IV TXA for Hemoptysis
Interventional Therapies for Acute PE – What We Know and What We Don’t
Anticoagulant Reversal Strategies and COI
FOCUS for Unstable PE
Focused cardiac ultrasound (FOCUS) is sensitive for detecting the presence of PE in those with a HR > 100bpm or systolic blood pressure <90 and highly sensitive for detection of PE in patients with a HR > 110bpm.
CRASH 3 – TXA for TBI
TXA appears to have a slight 28-day mortality benefit in traumatic brain injury (TBI) patients with a GCS ≥9, especially when given early.
Low-Dose Radiation and Cancer Risk in Kids
The incidence of cancer was higher in children exposed to low-dose diagnostic radiation than to non-exposed children. Be circumspect in scanning kids.
Outpatient Treatment of Febrile Neutropenia?
It appears that there is no difference in treatment failure or mortality when low-risk febrile neutropenia patients are treated at home vs inpatient. But be very cautious about this.
TXA vs Packing for Epistaxis
Intranasal tranexamic acid with nasal compression was as effective as Merocel nasal packing for bleeding cessation in anterior epistaxis, had a lower rebleeding rate, and was better tolerated than nasal packing.
New IDSA Guideline on Asymptomatic Bacteriuria
The IDSA now only recommends screening for and treating asymptomatic bacteriuria (ASB) in pregnant women and those undergoing an invasive urologic procedure.